2hqf: Difference between revisions
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==Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway== | |||
<StructureSection load='2hqf' size='340' side='right'caption='[[2hqf]], [[Resolution|resolution]] 3.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2hqf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.38Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqf OCA], [https://pdbe.org/2hqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqf RCSB], [https://www.ebi.ac.uk/pdbsum/2hqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqf ProSAT]</span></td></tr> | |||
== | </table> | ||
[[2hqf]] is a 1 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> | |||
== | == Evolutionary Conservation == | ||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[Category: Escherichia coli | Check<jmol> | ||
[[Category: Gu | <jmolCheckbox> | ||
[[Category: Li | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqf_consurf.spt"</scriptWhenChecked> | ||
[[Category: McDermott | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: Nikaido | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: Su | </jmolCheckbox> | ||
[[Category: Takatsuka | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqf ConSurf]. | ||
[[Category: Yu | <div style="clear:both"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Gu R]] | |||
[[Category: Li M]] | |||
[[Category: McDermott G]] | |||
[[Category: Nikaido H]] | |||
[[Category: Su C-C]] | |||
[[Category: Takatsuka Y]] | |||
[[Category: Yu EW]] | |||
Latest revision as of 09:34, 14 February 2024
Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway
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