2p7z: Difference between revisions

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{{Seed}}
[[Image:2p7z.png|left|200px]]


<!--
==Estrogen Related Receptor Gamma in complex with 4-hydroxy-tamoxifen==
The line below this paragraph, containing "STRUCTURE_2p7z", creates the "Structure Box" on the page.
<StructureSection load='2p7z' size='340' side='right'caption='[[2p7z]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2p7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P7Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene></td></tr>
{{STRUCTURE_2p7z| PDB=2p7z |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p7z OCA], [https://pdbe.org/2p7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p7z RCSB], [https://www.ebi.ac.uk/pdbsum/2p7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p7z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/2p7z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p7z ConSurf].
<div style="clear:both"></div>


===Estrogen Related Receptor Gamma in complex with 4-hydroxy-tamoxifen===
==See Also==
 
*[[Estrogen-related receptor 3D structures|Estrogen-related receptor 3D structures]]
 
== References ==
<!--  
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_17964775}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 17964775 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_17964775}}
 
==About this Structure==
2P7Z is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7Z OCA].
 
==Reference==
<ref group="xtra">PMID:17964775</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Abad, M C.]]
[[Category: Large Structures]]
[[Category: Hormone receptor]]
[[Category: Abad MC]]
[[Category: Three layered alpha helical sandwich]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:44:19 2009''

Latest revision as of 09:08, 21 February 2024

Estrogen Related Receptor Gamma in complex with 4-hydroxy-tamoxifen

2p7z, resolution 2.50Å

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