2qst: Difference between revisions

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{{Seed}}
[[Image:2qst.png|left|200px]]


<!--
==Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)==
The line below this paragraph, containing "STRUCTURE_2qst", creates the "Structure Box" on the page.
<StructureSection load='2qst' size='340' side='right'caption='[[2qst]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QST FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qst OCA], [https://pdbe.org/2qst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qst RCSB], [https://www.ebi.ac.uk/pdbsum/2qst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qst ProSAT]</span></td></tr>
{{STRUCTURE_2qst|  PDB=2qst  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)===
[https://www.uniprot.org/uniprot/CEAM5_HUMAN CEAM5_HUMAN] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.<ref>PMID:10864933</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_18086185}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18086185 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qst_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18086185}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qst ConSurf].
2QST is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:18086185</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Korotkova, N.]]
[[Category: Large Structures]]
[[Category: Moseley, S L.]]
[[Category: Korotkova N]]
[[Category: Stenkamp, R E.]]
[[Category: Le Trong I]]
[[Category: Trong, I Le.]]
[[Category: Moseley SL]]
[[Category: Cell adhesion]]
[[Category: Stenkamp RE]]
[[Category: Glycoprotein]]
[[Category: Gpi-anchor]]
[[Category: Immunoglobulin domain]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Polymorphism]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:08:08 2009''

Latest revision as of 09:17, 21 February 2024

Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)

2qst, resolution 2.90Å

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