3bf0: Difference between revisions

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{{Seed}}
[[Image:3bf0.png|left|200px]]


<!--
==Crystal structure of Escherichia coli Signal peptide peptidase (SppA), Native crystals==
The line below this paragraph, containing "STRUCTURE_3bf0", creates the "Structure Box" on the page.
<StructureSection load='3bf0' size='340' side='right'caption='[[3bf0]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3bf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BF0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bf0 OCA], [https://pdbe.org/3bf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bf0 RCSB], [https://www.ebi.ac.uk/pdbsum/3bf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bf0 ProSAT]</span></td></tr>
{{STRUCTURE_3bf0|  PDB=3bf0  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of Escherichia coli Signal peptide peptidase (SppA), Native crystals===
[https://www.uniprot.org/uniprot/SPPA_ECOLI SPPA_ECOLI] Digests cleaved signal peptides in vitro, its in vivo function is unknown. This activity is necessary to maintain proper secretion of mature proteins across the membrane.<ref>PMID:3522590</ref> <ref>PMID:18476724</ref> <ref>PMID:21810987</ref> <ref>PMID:18164727</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_18164727}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18164727 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/3bf0_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18164727}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bf0 ConSurf].
3BF0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BF0 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Crystal structure of a bacterial signal Peptide peptidase., Kim AC, Oliver DC, Paetzel M, J Mol Biol. 2008 Feb 15;376(2):352-66. Epub 2007 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18164727 18164727]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Paetzel, M.]]
[[Category: Paetzel M]]
[[Category: Bacterial]]
[[Category: Hydrolase]]
[[Category: Inner membrane]]
[[Category: Membrane]]
[[Category: Protease]]
[[Category: Ser/lys protease]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:23:26 2008''
Retrieved from "https://proteopedia.org/3bf0"