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[[Image:3cbh.png|left|200px]]


{{STRUCTURE_3cbh|  PDB=3cbh  |  SCENE=  }}
==THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI==
 
<StructureSection load='3cbh' size='340' side='right'caption='[[3cbh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3cbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CBH FirstGlance]. <br>
{{ABSTRACT_PUBMED_2377893}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cbh OCA], [https://pdbe.org/3cbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cbh RCSB], [https://www.ebi.ac.uk/pdbsum/3cbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cbh ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3cbh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBH OCA].  
== Function ==
[https://www.uniprot.org/uniprot/GUX2_HYPJE GUX2_HYPJE] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cb/3cbh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cbh ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cellobiohydrolase|Cellobiohydrolase]]
*[[Cellobiohydrolase 3D structures|Cellobiohydrolase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:002377893</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Cellulose 1,4-beta-cellobiosidase]]
[[Category: Trichoderma reesei]]
[[Category: Trichoderma reesei]]
[[Category: Jones, T A.]]
[[Category: Jones TA]]
[[Category: Rouvinen, J.]]
[[Category: Rouvinen J]]

Latest revision as of 09:34, 21 February 2024

THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI

3cbh, resolution 2.00Å

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