3dfx: Difference between revisions

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[[Image:3dfx.png|left|200px]]


{{STRUCTURE_3dfx|  PDB=3dfx  |  SCENE=  }}
==Opposite GATA DNA binding==
 
<StructureSection load='3dfx' size='340' side='right'caption='[[3dfx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Opposite GATA DNA binding===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3dfx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DFX FirstGlance]. <br>
{{ABSTRACT_PUBMED_18621058}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dfx OCA], [https://pdbe.org/3dfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dfx RCSB], [https://www.ebi.ac.uk/pdbsum/3dfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dfx ProSAT]</span></td></tr>
[[3dfx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFX OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/GATA3_MOUSE GATA3_MOUSE] Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
<ref group="xtra">PMID:018621058</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dfx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dfx ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Bates, D L.]]
[[Category: Bates DL]]
[[Category: Chen, L.]]
[[Category: Chen L]]
[[Category: Guo, L.]]
[[Category: Guo L]]
[[Category: Kim, G K.]]
[[Category: Kim GK]]
[[Category: Activator]]
[[Category: Dna-binding]]
[[Category: Metal-binding]]
[[Category: Nucleus]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription-dna complex]]
[[Category: Zinc-finger]]