3djf: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
m Protected "3djf" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3djf.png|left|200px]]


{{STRUCTURE_3djf| PDB=3djf | SCENE= }}
==Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34==
<StructureSection load='3djf' size='340' side='right'caption='[[3djf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3djf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DJF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.302&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BC3:2-AMINO-7-(PYRIDIN-3-YLMETHYL)-3,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE'>BC3</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3djf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3djf OCA], [https://pdbe.org/3djf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3djf RCSB], [https://www.ebi.ac.uk/pdbsum/3djf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3djf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9BMI9_SCHMA Q9BMI9_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/3djf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3djf ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34===
==See Also==
 
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
{{ABSTRACT_PUBMED_20129792}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[3djf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DJF OCA].
 
==Reference==
<ref group="xtra">PMID:020129792</ref><references group="xtra"/>
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Schistosoma mansoni]]
[[Category: Schistosoma mansoni]]
[[Category: Andricopulo, A D.]]
[[Category: Andricopulo AD]]
[[Category: Oliva, G.]]
[[Category: Oliva G]]
[[Category: Pereira, H M.]]
[[Category: Pereira HM]]
[[Category: Postigo, M P.]]
[[Category: Postigo MP]]
[[Category: Bcx34]]
[[Category: Glycosyltransferase]]
[[Category: Inhibitor]]
[[Category: Purine nucleoside phosphorylase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3djf"