3ea3: Difference between revisions

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{{Seed}}
[[Image:3ea3.png|left|200px]]


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==Crystal Structure of the Y246S/Y247S/Y248S/Y251S Mutant of Phosphatidylinositol-Specific Phospholipase C from Bacillus Thuringiensis==
The line below this paragraph, containing "STRUCTURE_3ea3", creates the "Structure Box" on the page.
<StructureSection load='3ea3' size='340' side='right'caption='[[3ea3]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ea3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EA3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_3ea3| PDB=3ea3 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ea3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ea3 OCA], [https://pdbe.org/3ea3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ea3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ea3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ea3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLC_BACTU PLC_BACTU] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/3ea3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ea3 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the Y246S/Y247S/Y248S/Y251S Mutant of Phosphatidylinositol-Specific Phospholipase C from Bacillus Thuringiensis===
==See Also==
 
*[[Phospholipase C|Phospholipase C]]
 
__TOC__
==About this Structure==
</StructureSection>
3EA3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EA3 OCA].
[[Category: Bacillus thuringiensis]]
[[Category: Bacillus thuringiensis]]
[[Category: Phosphatidylinositol diacylglycerol-lyase]]
[[Category: Large Structures]]
[[Category: Head, J F.]]
[[Category: Head JF]]
[[Category: Redfied, A G.]]
[[Category: Redfied AG]]
[[Category: Roberts, M F.]]
[[Category: Roberts MF]]
[[Category: Seaton, B A.]]
[[Category: Seaton BA]]
[[Category: Shao, C.]]
[[Category: Shao C]]
[[Category: Shi, X.]]
[[Category: Shi X]]
[[Category: Zambonelli, C.]]
[[Category: Zambonelli C]]
[[Category: Zhang, X.]]
[[Category: Zhang X]]
[[Category: Dimer]]
[[Category: Interfacially impaired]]
[[Category: Lipid degradation]]
[[Category: Lyase]]
[[Category: Membrane binding]]
[[Category: Phosphatidylinositol-specific phospholipase c]]
[[Category: Pi-plc]]
[[Category: Secreted]]
[[Category: Tim barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 21:32:51 2009''