3i3a: Difference between revisions

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{{Seed}}
[[Image:3i3a.jpg|left|200px]]


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==Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA==
The line below this paragraph, containing "STRUCTURE_3i3a", creates the "Structure Box" on the page.
<StructureSection load='3i3a' size='340' side='right'caption='[[3i3a]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3i3a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I3A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S2N:S-[2-({N-[(2R)-2-HYDROXY-4-{[(S)-HYDROXY(METHOXY)PHOSPHORYL]OXY}-3,3-DIMETHYLBUTANOYL]-BETA-ALANYL}AMINO)ETHYL]+(3R)-3-HYDROXYDODECANETHIOATE'>S2N</scene></td></tr>
{{STRUCTURE_3i3a| PDB=3i3a |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i3a OCA], [https://pdbe.org/3i3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i3a RCSB], [https://www.ebi.ac.uk/pdbsum/3i3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i3a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8EZA6_LEPIN Q8EZA6_LEPIN] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[SAAS:SAAS00064151]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/3i3a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i3a ConSurf].
<div style="clear:both"></div>


===Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA===
==See Also==
 
*[[UDP-N-acetylglucosamine acyltransferase|UDP-N-acetylglucosamine acyltransferase]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_19456129}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 19456129 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_19456129}}
 
==About this Structure==
3I3A is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I3A OCA].
 
==Reference==
<ref group="xtra">PMID:19456129</ref><references group="xtra"/>
[[Category: Leptospira interrogans]]
[[Category: Leptospira interrogans]]
[[Category: Williams, A H.]]
[[Category: Williams AH]]
[[Category: Acyltransferase]]
[[Category: Leptospira interrogan]]
[[Category: Leptospira interrogans complex]]
[[Category: Lipid a biosynthesis]]
[[Category: Lipid synthesis]]
[[Category: Lpxa]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep  3 15:58:03 2009''
Retrieved from "https://proteopedia.org/3i3a"