3j2u: Difference between revisions
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The | ==Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule== | ||
<SX load='3j2u' size='340' side='right' viewer='molstar' caption='[[3j2u]], [[Resolution|resolution]] 10.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3j2u]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. The July 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Microtubules'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_7 10.2210/rcsb_pdb/mom_2014_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J2U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2u OCA], [https://pdbe.org/3j2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j2u RCSB], [https://www.ebi.ac.uk/pdbsum/3j2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KI10A_DROME KI10A_DROME] Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux".<ref>PMID:14681690</ref> | |||
==See Also== | |||
*[[Kinesin 3D Structures|Kinesin 3D Structures]] | |||
*[[Tubulin 3D Structures|Tubulin 3D Structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Bos taurus]] | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Large Structures]] | |||
[[Category: Microtubules]] | |||
[[Category: RCSB PDB Molecule of the Month]] | |||
[[Category: Asenjo AB]] | |||
[[Category: Chatterjee C]] | |||
[[Category: DePaoli V]] | |||
[[Category: Diaz-Avalos R]] | |||
[[Category: Rice WJ]] | |||
[[Category: Silvestry M]] | |||
[[Category: Sosa H]] | |||
[[Category: Tan D]] | |||