3otb: Difference between revisions

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{{Seed}}
[[Image:3otb.jpg|left|200px]]


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==Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex==
The line below this paragraph, containing "STRUCTURE_3otb", creates the "Structure Box" on the page.
<StructureSection load='3otb' size='340' side='right'caption='[[3otb]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3otb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3otb|  PDB=3otb  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otb OCA], [https://pdbe.org/3otb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otb RCSB], [https://www.ebi.ac.uk/pdbsum/3otb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otb ProSAT]</span></td></tr>
 
</table>
===Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex===
== Function ==
 
[https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref>
 
== References ==
==About this Structure==
<references/>
3OTB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTB OCA].  
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Doublie, S.]]
[[Category: Large Structures]]
[[Category: Eckenroth, B E.]]
[[Category: Doublie S]]
[[Category: Hyde, S J.]]
[[Category: Eckenroth BE]]
[[Category: Catalytic carboxylate]]
[[Category: Hyde SJ]]
[[Category: Guanylyltransferase]]
[[Category: Polymerase-like palm domain]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:54:01 2010''