3otb: Difference between revisions
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== | ==Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex== | ||
[[ | <StructureSection load='3otb' size='340' side='right'caption='[[3otb]], [[Resolution|resolution]] 2.95Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3otb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTB FirstGlance]. <br> | ||
[[3otb]] is a 2 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otb OCA], [https://pdbe.org/3otb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otb RCSB], [https://www.ebi.ac.uk/pdbsum/3otb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otb ProSAT]</span></td></tr> | ||
< | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Doublie S]] | ||
[[Category: Eckenroth BE]] | |||
[[Category: | [[Category: Hyde SJ]] | ||
[[Category: | |||
Latest revision as of 10:36, 21 February 2024
Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex
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