3pja: Difference between revisions

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'''Unreleased structure'''


The entry 3pja is ON HOLD
==Crystal structure of human C3PO complex==
 
<StructureSection load='3pja' size='340' side='right'caption='[[3pja]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
Authors: Huang, N., Zhang, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3pja]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJA FirstGlance]. <br>
Description: Crystal structure of human C3PO complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pja OCA], [https://pdbe.org/3pja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pja RCSB], [https://www.ebi.ac.uk/pdbsum/3pja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pja ProSAT]</span></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:58:01 2010''
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>  Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Huang N]]
[[Category: Zhang H]]
Retrieved from "https://proteopedia.org/3pja"