3pp2: Difference between revisions
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New page: '''Unreleased structure''' The entry 3pp2 is ON HOLD Authors: Shen, L., Tempel, W., Tong, Y., Nedyalkova, L., Li, Y., Wernimont, A.K., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weig... |
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==Crystal structure of the pleckstrin homology domain of ArhGAP27== | |||
<StructureSection load='3pp2' size='340' side='right'caption='[[3pp2]], [[Resolution|resolution]] 1.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pp2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PP2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.421Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pp2 OCA], [https://pdbe.org/3pp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pp2 RCSB], [https://www.ebi.ac.uk/pdbsum/3pp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pp2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RHG27_HUMAN RHG27_HUMAN] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | |||
==See Also== | |||
*[[Rho GTPase activating protein 3D structures|Rho GTPase activating protein 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Edwards AM]] | |||
[[Category: Li Y]] | |||
[[Category: Nedyalkova L]] | |||
[[Category: Park H]] | |||
[[Category: Shen L]] | |||
[[Category: Tempel W]] | |||
[[Category: Tong Y]] | |||
[[Category: Weigelt J]] | |||
[[Category: Wernimont AK]] | |||
Latest revision as of 10:42, 21 February 2024
Crystal structure of the pleckstrin homology domain of ArhGAP27
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