3ql3: Difference between revisions

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[[Image:3ql3.png|left|200px]]


{{STRUCTURE_3ql3|  PDB=3ql3  |  SCENE=  }}
==Re-refined coordinates for PDB entry 1RX2==
 
<StructureSection load='3ql3' size='340' side='right'caption='[[3ql3]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Re-refined coordinates for PDB entry 1RX2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ql3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QL3 FirstGlance]. <br>
{{ABSTRACT_PUBMED_9012674}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ql3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ql3 OCA], [https://pdbe.org/3ql3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ql3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ql3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ql3 ProSAT]</span></td></tr>
[[3ql3]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QL3 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


==See Also==
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009012674</ref><ref group="xtra">PMID:021474759</ref><references group="xtra"/>
[[Category: Escherichia coli K-12]]
[[Category: Dihydrofolate reductase]]
[[Category: Large Structures]]
[[Category: Escherichia coli]]
[[Category: Bhabha G]]
[[Category: Bhabha, G.]]
[[Category: Ekiert DC]]
[[Category: Ekiert, D C.]]
[[Category: Wilson IA]]
[[Category: Wilson, I A.]]
[[Category: Wright PE]]
[[Category: Wright, P E.]]
[[Category: Cofactor]]
[[Category: Dihydrofolate]]
[[Category: Nadph]]
[[Category: Oxidoreductase]]
[[Category: Rossman fold]]
[[Category: Tetrahydrofolate]]
Retrieved from "https://proteopedia.org/3ql3"