402d: Difference between revisions

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[[Image:402d.gif|left|200px]]


{{Structure
==5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'==
|PDB= 402d |SIZE=350|CAPTION= <scene name='initialview01'>402d</scene>, resolution 2.300&Aring;
<StructureSection load='402d' size='340' side='right'caption='[[402d]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
<table><tr><td colspan='2'>[[402d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=402D FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=402d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=402d OCA], [https://pdbe.org/402d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=402d RCSB], [https://www.ebi.ac.uk/pdbsum/402d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=402d ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
__TOC__
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=402d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=402d OCA], [http://www.ebi.ac.uk/pdbsum/402d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=402d RCSB]</span>
</StructureSection>
}}
[[Category: Large Structures]]
 
[[Category: Carter R]]
'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3''''
[[Category: Chi Y-I]]
 
[[Category: Holbrook EL]]
 
[[Category: Holbrook SR]]
==Overview==
[[Category: Hung L-W]]
The crystal structure of the RNA octamer 5'-CGC(CA)GCG-3' has been determined from X-ray diffraction data to 2.3 A resolution. In the crystal, this oligomer forms a self-complementary double helix in the asymmetric unit. Tandem non-Watson-Crick C-A and A-C base pairs comprise an internal loop in the middle of the duplex, which is incorporated with little distortion of the A-form double helix. From the geometry of the C-A base pairs, it is inferred that the adenosine imino group is protonated and donates a hydrogen bond to the carbonyl group of the cytosine. The wobble geometry of the C-A+ base pairs is very similar to that of the common U-G non-Watson-Crick pair.
[[Category: Jang SB]]
 
==About this Structure==
402D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA].
 
==Reference==
Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295]
[[Category: Protein complex]]
[[Category: Carter, R.]]
[[Category: Chi, Y I.]]
[[Category: Holbrook, E L.]]
[[Category: Holbrook, S R.]]
[[Category: Hung, L W.]]
[[Category: Jang, S B.]]
[[Category: rna double helix]]
[[Category: rna with tandem c-a+ base pair]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:36:45 2008''
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