4en2: Difference between revisions

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[[Image:4en2.jpg|left|200px]]


{{STRUCTURE_4en2| PDB=4en2 | SCENE= }}
==HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)==
<StructureSection load='4en2' size='340' side='right'caption='[[4en2]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4en2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EN2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4en2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4en2 OCA], [https://pdbe.org/4en2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4en2 RCSB], [https://www.ebi.ac.uk/pdbsum/4en2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4en2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AP1M1_MOUSE AP1M1_MOUSE] Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.


===HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)===
==See Also==
 
*[[Adaptin 3D structures|Adaptin 3D structures]]
 
*[[Protein Nef 3D structures|Protein Nef 3D structures]]
==About this Structure==
__TOC__
[[4en2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN2 OCA].
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Jia, X.]]
[[Category: Jia X]]
[[Category: Xiong, Y.]]
[[Category: Xiong Y]]
[[Category: Adaptor protein complex 1]]
[[Category: Antigen presentation]]
[[Category: Clasp]]
[[Category: Hiv]]
[[Category: Host defense]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Membrane trafficking]]
[[Category: Mhc-i]]
[[Category: Mu1 adaptin subunit]]
[[Category: Nef]]
[[Category: Sorting motif recognition]]
[[Category: Viral hijacking]]
[[Category: Viral protein-immune system complex]]
Retrieved from "https://proteopedia.org/4en2"