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[[Image:4esj.png|left|200px]]


{{STRUCTURE_4esj|  PDB=4esj  |  SCENE=  }}
==RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA==
 
<StructureSection load='4esj' size='340' side='right'caption='[[4esj]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
===RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4esj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESJ FirstGlance]. <br>
{{ABSTRACT_PUBMED_22610857}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6MA:N6-METHYL-DEOXY-ADENOSINE-5-MONOPHOSPHATE'>6MA</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esj OCA], [https://pdbe.org/4esj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esj RCSB], [https://www.ebi.ac.uk/pdbsum/4esj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esj ProSAT]</span></td></tr>
[[4esj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESJ OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/T2D1_STRR6 T2D1_STRR6] Recognizes the double-stranded and methylated sequence G(Me)ATC and cleaves after A-2.
<ref group="xtra">PMID:022610857</ref><references group="xtra"/>
__TOC__
[[Category: Streptococcus pneumoniae tigr4]]
</StructureSection>
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Large Structures]]
[[Category: Bochtler, M.]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Bujnicki, J M.]]
[[Category: Synthetic construct]]
[[Category: Czapinska, H.]]
[[Category: Bochtler M]]
[[Category: Siwek, W.]]
[[Category: Bujnicki JM]]
[[Category: Skowronek, K.]]
[[Category: Czapinska H]]
[[Category: Dna binding]]
[[Category: Siwek W]]
[[Category: Dpni]]
[[Category: Skowronek K]]
[[Category: Hydrolase-dna complex]]
[[Category: Methylation dependent]]
[[Category: N6-methyladenine]]
[[Category: Restriction endonuclease]]
[[Category: Restriction endonuclease-dna complex]]
[[Category: Restriction enzyme]]
[[Category: Type iie]]
[[Category: Type iim]]
[[Category: Winged helix domain]]