4eza: Difference between revisions
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New page: '''Unreleased structure''' The entry 4eza is ON HOLD Authors: Van Aalten, D.M., Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C... |
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==Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2== | |||
<StructureSection load='4eza' size='340' side='right'caption='[[4eza]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4eza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eza OCA], [https://pdbe.org/4eza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eza RCSB], [https://www.ebi.ac.uk/pdbsum/4eza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eza ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Agacan M]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Batty IH]] | |||
[[Category: Bochkarev A]] | |||
[[Category: Bountra C]] | |||
[[Category: Crombet L]] | |||
[[Category: Dixon MJ]] | |||
[[Category: Downes CP]] | |||
[[Category: Edwards AM]] | |||
[[Category: Gray A]] | |||
[[Category: Leslie NR]] | |||
[[Category: Nedyalkova L]] | |||
[[Category: Park H]] | |||
[[Category: Schenning M]] | |||
[[Category: Tempel W]] | |||
[[Category: Tong Y]] | |||
[[Category: Van Aalten DMF]] | |||
[[Category: Weigelt J]] | |||
[[Category: Zhong N]] | |||
Latest revision as of 11:07, 1 March 2024
Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2
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