4gfd: Difference between revisions
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==Thymidylate kinase (TMK) from S. Aureus in complex with TK-666== | |||
<StructureSection load='4gfd' size='340' side='right'caption='[[4gfd]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gfd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0YB:2-(3-BROMOPHENOXY)-4-{(1R)-3,3-DIMETHYL-1-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]BUTYL}BENZOIC+ACID'>0YB</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfd OCA], [https://pdbe.org/4gfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfd RCSB], [https://www.ebi.ac.uk/pdbsum/4gfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfd ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | |||
===Thymidylate kinase | ==See Also== | ||
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[ | [[Category: Staphylococcus aureus subsp. aureus N315]] | ||
[[Category: Staphylococcus aureus subsp. aureus | [[Category: Keating T]] | ||
[[Category: Martinez-Botella G]] | |||
[[Category: Keating | [[Category: Olivier NB]] | ||
[[Category: Martinez-Botella | |||
[[Category: Olivier | |||
Latest revision as of 11:28, 1 March 2024
Thymidylate kinase (TMK) from S. Aureus in complex with TK-666
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