4gfl: Difference between revisions
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==NO mechanism, slma== | |||
<StructureSection load='4gfl' size='340' side='right'caption='[[4gfl]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gfl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfl OCA], [https://pdbe.org/4gfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfl RCSB], [https://www.ebi.ac.uk/pdbsum/4gfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfl ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SLMA_KLEP3 SLMA_KLEP3] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Klebsiella pneumoniae 342]] | |||
[[Category: Large Structures]] | |||
[[Category: Schumacher MA]] | |||
