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New page: '''Unreleased structure''' The entry 4has is ON HOLD Authors: Froese, D.S., Krojer, T., Strain-Damerell, C., Allerston, C., Kiyani, W., Burgess-Brown, N., von Delft, F., Arrowsmith, C.,...
 
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'''Unreleased structure'''


The entry 4has is ON HOLD
==Crystal structure of PX domain of human sorting nexin SNX27==
<StructureSection load='4has' size='340' side='right'caption='[[4has]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4has]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HAS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4has FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4has OCA], [https://pdbe.org/4has PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4has RCSB], [https://www.ebi.ac.uk/pdbsum/4has PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4has ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SNX27_HUMAN SNX27_HUMAN] Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity).<ref>PMID:17351151</ref>


Authors: Froese, D.S., Krojer, T., Strain-Damerell, C., Allerston, C., Kiyani, W., Burgess-Brown, N., von Delft, F., Arrowsmith, C., Bountra, C., Edwards, A., Yue, W.W., Structural Genomics Consortium (SGC)
==See Also==
 
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
Description: Crystal structure of PX domain of human sorting nexin SNX27
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Allerston C]]
[[Category: Arrowsmith C]]
[[Category: Bountra C]]
[[Category: Burgess-Brown N]]
[[Category: Edwards A]]
[[Category: Froese DS]]
[[Category: Kiyani W]]
[[Category: Krojer T]]
[[Category: Strain-Damerell C]]
[[Category: Yue WW]]
[[Category: Von Delft F]]
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