4jmr: Difference between revisions
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New page: '''Unreleased structure''' The entry 4jmr is ON HOLD Authors: Taylor, I.A., Goldstone, D.C., Flower, T.G., Ball, N.J. Description: A unique spumavirus gag N-terminal domain with functi... |
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==A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid== | |||
<StructureSection load='4jmr' size='340' side='right'caption='[[4jmr]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4jmr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_foamy_virus Human foamy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JMR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jmr OCA], [https://pdbe.org/4jmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jmr RCSB], [https://www.ebi.ac.uk/pdbsum/4jmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jmr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GAG_FOAMV GAG_FOAMV] Involved in capsid formation and genome binding. Shortly after infection, interaction between incoming particle-associated Gag proteins and host dynein allows centrosomal targeting of the viral genome (associated to Gag), prior to nucleus translocation and integration into host genome.<ref>PMID:16160174</ref> <ref>PMID:12857789</ref> | |||
==See Also== | |||
*[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human foamy virus]] | |||
[[Category: Large Structures]] | |||
[[Category: Ball NJ]] | |||
[[Category: Flower TG]] | |||
[[Category: Goldstone DC]] | |||
[[Category: Taylor IA]] | |||
