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{{STRUCTURE_4lpb|  PDB=4lpb  |  SCENE=  }}
===Crystal structure of a topoisomerase ATPase inhibitor===
{{ABSTRACT_PUBMED_24098982}}


==About this Structure==
==Crystal structure of a topoisomerase ATPase inhibitor==
[[4lpb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPB OCA].  
<StructureSection load='4lpb' size='340' side='right'caption='[[4lpb]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4lpb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LPB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YP:1-ETHYL-3-{5-(5-OXO-4,5-DIHYDRO-1,3,4-OXADIAZOL-2-YL)-4-[4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-YL]-3,3-BIPYRIDIN-6-YL}UREA'>1YP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lpb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lpb OCA], [https://pdbe.org/4lpb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lpb RCSB], [https://www.ebi.ac.uk/pdbsum/4lpb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lpb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8DQB5_STRR6 Q8DQB5_STRR6]


==Reference==
==See Also==
<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/>
*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
[[Category: Streptococcus pneumoniae r6]]
__TOC__
[[Category: Boriack-Sjodin, A.]]
</StructureSection>
[[Category: Antimicrobial]]
[[Category: Large Structures]]
[[Category: Atp binding]]
[[Category: Streptococcus pneumoniae R6]]
[[Category: Atp binding domain]]
[[Category: Boriack-Sjodin A]]
[[Category: Isomerase-isomerase inhibitor complex]]
[[Category: Protein-inhibitor complex]]
[[Category: Structure-based drug design]]
[[Category: Virtual screen]]
Retrieved from "https://proteopedia.org/4lpb"