4lry: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_4lry|  PDB=4lry  |  SCENE=  }}
===Crystal Structure of the E.coli DhaR(N)-DhaK(T79L) complex===
{{ABSTRACT_PUBMED_24440518}}


==Function==
==Crystal Structure of the E.coli DhaR(N)-DhaK(T79L) complex==
[[http://www.uniprot.org/uniprot/DHAK_ECOLI DHAK_ECOLI]] Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of DhaR by binding to its sensor domain, in the absence of dihydroxyacetone. [[http://www.uniprot.org/uniprot/DHAR_ECOLI DHAR_ECOLI]] Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own synthesis.
<StructureSection load='4lry' size='340' side='right'caption='[[4lry]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4lry]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LRY FirstGlance]. <br>
[[4lry]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRY OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lry OCA], [https://pdbe.org/4lry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lry RCSB], [https://www.ebi.ac.uk/pdbsum/4lry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lry ProSAT]</span></td></tr>
<ref group="xtra">PMID:024440518</ref><references group="xtra"/><references/>
</table>
[[Category: Cygler, M.]]
== Function ==
[[Category: Ekiel, I.]]
[https://www.uniprot.org/uniprot/DHAK_ECOLI DHAK_ECOLI] Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of DhaR by binding to its sensor domain, in the absence of dihydroxyacetone.
[[Category: McDonald, L.]]
__TOC__
[[Category: Shi, R.]]
</StructureSection>
[[Category: Coiled-coil]]
[[Category: Escherichia coli K-12]]
[[Category: Gaf]]
[[Category: Large Structures]]
[[Category: Helix rotation]]
[[Category: Cygler M]]
[[Category: Pa]]
[[Category: Ekiel I]]
[[Category: Transcriptional regulation complex]]
[[Category: McDonald L]]
[[Category: Transferase-transcription regulator complex]]
[[Category: Shi R]]
Retrieved from "https://proteopedia.org/4lry"