4m2s: Difference between revisions
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New page: '''Unreleased structure''' The entry 4m2s is ON HOLD Authors: Li, J., Jaimes, K.F., Aller, S.G. Description: Corrected Structure of Mouse P-glycprotein |
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==Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR== | |||
<StructureSection load='4m2s' size='340' side='right'caption='[[4m2s]], [[Resolution|resolution]] 4.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4m2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M2S FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JZ:(4R,11R,18R)-4,11,18-TRI(PROPAN-2-YL)-6,13,20-TRISELENA-3,10,17,22,23,24-HEXAAZATETRACYCLO[17.2.1.1~5,8~.1~12,15~]TETRACOSA-1(21),5(24),7,12(23),14,19(22)-HEXAENE-2,9,16-TRIONE'>0JZ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m2s OCA], [https://pdbe.org/4m2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m2s RCSB], [https://www.ebi.ac.uk/pdbsum/4m2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m2s ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Aller SG]] | |||
[[Category: Jaimes KF]] | |||
[[Category: Li J]] | |||
Latest revision as of 12:23, 1 March 2024
Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
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