4mcb: Difference between revisions

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{{STRUCTURE_4mcb|  PDB=4mcb  |  SCENE=  }}
===H.influenzae TrmD in complex with N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE===
{{ABSTRACT_PUBMED_23981144}}


==Function==
==H.influenzae TrmD in complex with N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE==
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]  
<StructureSection load='4mcb' size='340' side='right'caption='[[4mcb]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mcb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MCB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=21W:N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE'>21W</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mcb OCA], [https://pdbe.org/4mcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mcb RCSB], [https://www.ebi.ac.uk/pdbsum/4mcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mcb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]


==About this Structure==
==See Also==
[[4mcb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae_rd_kw20 Haemophilus influenzae rd kw20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MCB OCA].
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:023981144</ref><references group="xtra"/><references/>
[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Haemophilus influenzae rd kw20]]
[[Category: Large Structures]]
[[Category: Hill, P.]]
[[Category: Hill P]]
[[Category: Olivier, N B.]]
[[Category: Olivier NB]]
[[Category: Hmt]]
[[Category: Methyl transferase to trna]]
[[Category: Sah]]
[[Category: Sam]]
[[Category: Sinefungin]]
[[Category: Structural genomic]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trefoil]]
[[Category: Trefoil knot]]
[[Category: Trmd]]
[[Category: Trna]]

Latest revision as of 12:25, 1 March 2024

H.influenzae TrmD in complex with N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE

4mcb, resolution 1.94Å

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