4mro: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 4mro is ON HOLD Authors: St. Jean, D. J., Ashton, K. S., Bartberger, M. D., Chen, J., Chmait, S., Cupples, R., Galbreath, E., Helmering, J., Jordan,... |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Human GKRP bound to AMG-5980 and S6P== | |||
<StructureSection load='4mro' size='340' side='right'caption='[[4mro]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4mro]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MRO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG0:2-(4-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]PIPERAZIN-1-YL}PHENYL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG0</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mro OCA], [https://pdbe.org/4mro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mro RCSB], [https://www.ebi.ac.uk/pdbsum/4mro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mro ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. | |||
==See Also== | |||
*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ashton KS]] | |||
[[Category: Bartberger MD]] | |||
[[Category: Chen J]] | |||
[[Category: Chmait S]] | |||
[[Category: Cupples R]] | |||
[[Category: Fotsch C]] | |||
[[Category: Galbreath E]] | |||
[[Category: Hale C]] | |||
[[Category: Helmering J]] | |||
[[Category: Jordan SR]] | |||
[[Category: Kunz K]] | |||
[[Category: LLoyd DJ]] | |||
[[Category: Liu L]] | |||
[[Category: Michelsen K]] | |||
[[Category: Nishimura N]] | |||
[[Category: Norman MH]] | |||
[[Category: Pennington LD]] | |||
[[Category: Poon SF]] | |||
[[Category: Sivits G]] | |||
[[Category: St Jean DJ]] | |||
[[Category: Stec MM]] | |||
[[Category: Tamayo N]] | |||
[[Category: Van G]] | |||
[[Category: Yang K]] | |||
Latest revision as of 12:28, 1 March 2024
Human GKRP bound to AMG-5980 and S6P
| ||||||||||||
