4n1a: Difference between revisions

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New page: '''Unreleased structure''' The entry 4n1a is ON HOLD Authors: Dovala, D.L., Bendebury, A, Cox, J.S., Stroud, R.M., Rosenberg, O.S. Description: Thermomonospora curvata protein complex
 
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'''Unreleased structure'''


The entry 4n1a is ON HOLD
==Thermomonospora curvata EccC (ATPases 2 and 3) in complex with a signal sequence peptide==
 
<StructureSection load='4n1a' size='340' side='right'caption='[[4n1a]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
Authors: Dovala, D.L., Bendebury, A, Cox, J.S., Stroud, R.M., Rosenberg, O.S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4n1a]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermomonospora_curvata_DSM_43183 Thermomonospora curvata DSM 43183]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1A FirstGlance]. <br>
Description: Thermomonospora curvata protein complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1a OCA], [https://pdbe.org/4n1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1a RCSB], [https://www.ebi.ac.uk/pdbsum/4n1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ECCC_THECD ECCC_THECD] Part of the ESX specialized secretion system, which exports proteins from the cell including EsxA (ESAT-6) and EsxB (CFP-10) (PubMed:25865481). Has weak intrinsic ATPase activity; probably only the first FtsK domain can hydrolyze ATP (PubMed:25865481). Might be the translocase subunit (PubMed:25865481).<ref>PMID:25865481</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermomonospora curvata DSM 43183]]
[[Category: Bendebury A]]
[[Category: Cox JS]]
[[Category: Dovala DL]]
[[Category: Rosenberg OS]]
[[Category: Stroud RM]]
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