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{{STRUCTURE_4oca|  PDB=4oca  |  SCENE=  }}
===Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N===
{{ABSTRACT_PUBMED_24460375}}


==Function==
==Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N==
[[http://www.uniprot.org/uniprot/F5ZUF5_SALTU F5ZUF5_SALTU]] Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).[HAMAP-Rule:MF_01167][SAAS:SAAS022850_004_033570]  
<StructureSection load='4oca' size='340' side='right'caption='[[4oca]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4oca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OCA FirstGlance]. <br>
[[4oca]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCA OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2QR:(2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr+an-2-yl+[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl+dihydrogen+diphosphate'>2QR</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oca OCA], [https://pdbe.org/4oca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oca RCSB], [https://www.ebi.ac.uk/pdbsum/4oca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oca ProSAT]</span></td></tr>
<ref group="xtra">PMID:024460375</ref><references group="xtra"/><references/>
</table>
[[Category: UDP-4-amino-4-deoxy-L-arabinose aminotransferase]]
__TOC__
[[Category: Lee, M.]]
</StructureSection>
[[Category: Sousa, M C.]]
[[Category: Large Structures]]
[[Category: Aminotransferase]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Transferase]]
[[Category: Lee M]]
[[Category: Sousa MC]]

Latest revision as of 12:39, 1 March 2024

Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N

4oca, resolution 2.30Å

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