4oep: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 4oep is ON HOLD~~

==Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail==

~~Authors: Nomme, J., Lavie, A.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4oep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OEP OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4OEP FirstGlance].

~~Description:~~ Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4oep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oep OCA], [https://pdbe.org/4oep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oep RCSB], [https://www.ebi.ac.uk/pdbsum/4oep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oep ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Lavie A]]

[[Category: Nomme J]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4oep is ON HOLD
+==Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail==
+<StructureSection load='4oep' size='340' side='right'caption='[[4oep]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-Authors: Nomme, J., Lavie, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4oep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OEP FirstGlance]. <br>
-Description: Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oep OCA], [https://pdbe.org/4oep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oep RCSB], [https://www.ebi.ac.uk/pdbsum/4oep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oep ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Lavie A]]
+[[Category: Nomme J]]