5eak: Difference between revisions
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New page: '''Unreleased structure''' The entry 5eak is ON HOLD until Paper Publication Authors: Su, H.P. Description: TITLE PENDING PUBLICATION Category: Unreleased Structures [[Category: Su... |
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==Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties== | |||
<StructureSection load='5eak' size='340' side='right'caption='[[5eak]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5eak]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EAK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=24R:N-[(1S,2R)-2-AMINOCYCLOHEXYL]-4-[6-(1-METHYL-1H-PYRAZOL-4-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]THIOPHENE-2-CARBOXAMIDE'>24R</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eak OCA], [https://pdbe.org/5eak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eak RCSB], [https://www.ebi.ac.uk/pdbsum/5eak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eak ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MARK2_HUMAN MARK2_HUMAN] | |||
==See Also== | |||
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Su | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Su HP]] | |||
Latest revision as of 12:27, 6 March 2024
Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties
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