5vc9: Difference between revisions
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==Zinc finger of human CXXC4 in complex with CpG DNA== | ==Zinc finger of human CXXC4 in complex with CpG DNA== | ||
<StructureSection load='5vc9' size='340' side='right' caption='[[5vc9]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='5vc9' size='340' side='right'caption='[[5vc9]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5vc9]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5vc9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VC9 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vc9 OCA], [https://pdbe.org/5vc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vc9 RCSB], [https://www.ebi.ac.uk/pdbsum/5vc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vc9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CXXC4_HUMAN CXXC4_HUMAN] Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: Liu K]] | ||
[[Category: | [[Category: Min J]] | ||
[[Category: Tempel W]] | |||
[[Category: | [[Category: Walker JR]] | ||
[[Category: | [[Category: Xu C]] | ||
[[Category: | |||
Latest revision as of 14:32, 6 March 2024
Zinc finger of human CXXC4 in complex with CpG DNA
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