1mw2: Difference between revisions

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{{Seed}}
[[Image:1mw2.png|left|200px]]


<!--
==Amylosucrase soaked with 100mM sucrose==
The line below this paragraph, containing "STRUCTURE_1mw2", creates the "Structure Box" on the page.
<StructureSection load='1mw2' size='340' side='right'caption='[[1mw2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mw2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_polysaccharea Neisseria polysaccharea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MW2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=PRD_900010:alpha-maltotetraose'>PRD_900010</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
{{STRUCTURE_1mw2| PDB=1mw2 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mw2 OCA], [https://pdbe.org/1mw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mw2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mw2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AMYS_NEIPO AMYS_NEIPO] Catalyzes the synthesis of alpha-glucan from sucrose. Catalyzes, in addition, sucrose hydrolysis, maltose and maltotriose synthesis by successive transfers of the glucosyl moiety of sucrose onto the released glucose, and finally turanose and trehalulose synthesis, these two sucrose isomers being obtained by glucosyl transfer onto fructose.<ref>PMID:9882648</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/1mw2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mw2 ConSurf].
<div style="clear:both"></div>


===Amylosucrase soaked with 100mM sucrose===
==See Also==
 
*[[Amylase 3D structures|Amylase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_12364331}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 12364331 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_12364331}}
 
==About this Structure==
1MW2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_polysaccharea Neisseria polysaccharea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MW2 OCA].
 
==Reference==
Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity., Skov LK, Mirza O, Sprogoe D, Dar I, Remaud-Simeon M, Albenne C, Monsan P, Gajhede M, J Biol Chem. 2002 Dec 6;277(49):47741-7. Epub 2002 Oct 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12364331 12364331]
[[Category: Amylosucrase]]
[[Category: Neisseria polysaccharea]]
[[Category: Neisseria polysaccharea]]
[[Category: Single protein]]
[[Category: Albenne C]]
[[Category: Albenne, C.]]
[[Category: Dar I]]
[[Category: Dar, I.]]
[[Category: Gajhede M]]
[[Category: Gajhede, M.]]
[[Category: Mirza O]]
[[Category: Mirza, O.]]
[[Category: Monsan P]]
[[Category: Monsan, P.]]
[[Category: Remaud-Simeon M]]
[[Category: Remaud-Simeon, M.]]
[[Category: Skov LK]]
[[Category: Skov, L K.]]
[[Category: Sprogoe D]]
[[Category: Sprogoe, D.]]
[[Category: Protein-sugar complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:25:10 2008''

Latest revision as of 13:27, 13 March 2024

Amylosucrase soaked with 100mM sucrose

1mw2, resolution 2.10Å

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