1wu3: Difference between revisions

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[[Image:1wu3.png|left|200px]]


{{STRUCTURE_1wu3|  PDB=1wu3  |  SCENE=  }}
==Crystal structure of recombinant murine interferon beta==
 
<StructureSection load='1wu3' size='340' side='right'caption='[[1wu3]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
===Crystal structure of recombinant murine interferon beta===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1wu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WU3 FirstGlance]. <br>
{{ABSTRACT_PUBMED_7473712}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu3 OCA], [https://pdbe.org/1wu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1wu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wu3 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1wu3]] is a 1 chain structure of [[Multiple sclerosis]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wu3 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Interferons|Interferons]]
*[[Interferon 3D structures|Interferon 3D structures]]
*[[Multiple sclerosis|Multiple sclerosis]]
*[[Multiple sclerosis|Multiple sclerosis]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:007473712</ref><ref group="xtra">PMID:001505514</ref><ref group="xtra">PMID:008415875</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Mitsui, Y.]]
[[Category: Mitsui Y]]
[[Category: Saitoh, S.]]
[[Category: Saitoh S]]
[[Category: Senda, T.]]
[[Category: Senda T]]
[[Category: Alpha-helix-bundle]]
[[Category: Cytokine]]
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