1wu3: Difference between revisions

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{{Seed}}
[[Image:1wu3.png|left|200px]]


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==Crystal structure of recombinant murine interferon beta==
The line below this paragraph, containing "STRUCTURE_1wu3", creates the "Structure Box" on the page.
<StructureSection load='1wu3' size='340' side='right'caption='[[1wu3]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1wu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WU3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu3 OCA], [https://pdbe.org/1wu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1wu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wu3 ProSAT]</span></td></tr>
{{STRUCTURE_1wu3| PDB=1wu3 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wu3 ConSurf].
<div style="clear:both"></div>


===Crystal structure of recombinant murine interferon beta===
==See Also==
 
*[[Interferon 3D structures|Interferon 3D structures]]
 
*[[Multiple sclerosis|Multiple sclerosis]]
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The line below this paragraph, {{ABSTRACT_PUBMED_7473712}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 7473712 is the PubMed ID number.
[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_7473712}}
 
==About this Structure==
1WU3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA].
 
==Reference==
Refined crystal structure of recombinant murine interferon-beta at 2.15 A resolution., Senda T, Saitoh S, Mitsui Y, J Mol Biol. 1995 Oct 13;253(1):187-207. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7473712 7473712]
 
Three-dimensional crystal structure of recombinant murine interferon-beta., Senda T, Shimazu T, Matsuda S, Kawano G, Shimizu H, Nakamura KT, Mitsui Y, EMBO J. 1992 Sep;11(9):3193-201. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1505514 1505514]
 
Structural, functional and evolutionary implications of the three-dimensional crystal structure of murine interferon-beta., Mitsui Y, Senda T, Shimazu T, Matsuda S, Utsumi J, Pharmacol Ther. 1993;58(1):93-132. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8415875 8415875]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Mitsui Y]]
[[Category: Mitsui, Y.]]
[[Category: Saitoh S]]
[[Category: Saitoh, S.]]
[[Category: Senda T]]
[[Category: Senda, T.]]
[[Category: Alpha-helix-bundle]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:23:53 2008''

Latest revision as of 13:34, 13 March 2024

Crystal structure of recombinant murine interferon beta

1wu3, resolution 2.15Å

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