2bd0: Difference between revisions

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{{Seed}}
[[Image:2bd0.png|left|200px]]


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==Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin==
The line below this paragraph, containing "STRUCTURE_2bd0", creates the "Structure Box" on the page.
<StructureSection load='2bd0' size='340' side='right'caption='[[2bd0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2bd0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum_TLS Chlorobaculum tepidum TLS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BD0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BIO:BIOPTERIN'>BIO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_2bd0|  PDB=2bd0  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bd0 OCA], [https://pdbe.org/2bd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bd0 RCSB], [https://www.ebi.ac.uk/pdbsum/2bd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bd0 ProSAT]</span></td></tr>
 
</table>
===Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin===
== Function ==
 
[https://www.uniprot.org/uniprot/SPRE_CHLTE SPRE_CHLTE] Catalyzes the final reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.<ref>PMID:10333495</ref> <ref>PMID:15621425</ref> <ref>PMID:18542834</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_16308317}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 16308317 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/2bd0_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16308317}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2BD0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BD0 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bd0 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Structure of Chlorobium tepidum sepiapterin reductase complex reveals the novel substrate binding mode for stereospecific production of L-threo-tetrahydrobiopterin., Supangat S, Seo KH, Choi YK, Park YS, Son D, Han CD, Lee KH, J Biol Chem. 2006 Jan 27;281(4):2249-56. Epub 2005 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16308317 16308317]
<references/>
[[Category: Chlorobaculum tepidum]]
__TOC__
[[Category: Sepiapterin reductase]]
</StructureSection>
[[Category: Single protein]]
[[Category: Chlorobaculum tepidum TLS]]
[[Category: Choi, Y K.]]
[[Category: Large Structures]]
[[Category: Lee, K H.]]
[[Category: Choi YK]]
[[Category: Park, Y S.]]
[[Category: Lee KH]]
[[Category: Seo, K H.]]
[[Category: Park YS]]
[[Category: Supangat, S.]]
[[Category: Seo KH]]
[[Category: Chlorobium tepidum]]
[[Category: Supangat S]]
[[Category: Sepiapterin reductase]]
 
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Retrieved from "https://proteopedia.org/2bd0"