2d1c: Difference between revisions

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[[Image:2d1c.gif|left|200px]]<br /><applet load="2d1c" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2d1c, resolution 1.80&Aring;" />
'''Crystal Structure Of TT0538 protein from Thermus thermophilus HB8'''<br />


==About this Structure==
==Crystal Structure Of TT0538 protein from Thermus thermophilus HB8==
2D1C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1C OCA].
<StructureSection load='2d1c' size='340' side='right'caption='[[2d1c]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
[[Category: Isocitrate dehydrogenase (NADP(+))]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2d1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D1C FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
[[Category: Kunishima, N.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Lokanath, N K.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d1c OCA], [https://pdbe.org/2d1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d1c RCSB], [https://www.ebi.ac.uk/pdbsum/2d1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d1c ProSAT], [https://www.topsan.org/Proteins/RSGI/2d1c TOPSAN]</span></td></tr>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
</table>
[[Category: CIT]]
== Function ==
[[Category: NAP]]
[https://www.uniprot.org/uniprot/IDH_THET8 IDH_THET8]  
[[Category: dehydrogenase]]
== Evolutionary Conservation ==
[[Category: national project on protein structural and functional analyses]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: nppsfa]]
Check<jmol>
[[Category: riken structural genomics/proteomics initiative]]
  <jmolCheckbox>
[[Category: rsgi]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/2d1c_consurf.spt"</scriptWhenChecked>
[[Category: structural genomics]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d1c ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:54:21 2008''
==See Also==
*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Kunishima N]]
[[Category: Lokanath NK]]