2d1p: Difference between revisions

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{{Seed}}
[[Image:2d1p.png|left|200px]]


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==crystal structure of heterohexameric TusBCD proteins, which are crucial for the tRNA modification==
The line below this paragraph, containing "STRUCTURE_2d1p", creates the "Structure Box" on the page.
<StructureSection load='2d1p' size='340' side='right'caption='[[2d1p]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2d1p]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D1P FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2d1p|  PDB=2d1p  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d1p OCA], [https://pdbe.org/2d1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d1p RCSB], [https://www.ebi.ac.uk/pdbsum/2d1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d1p ProSAT]</span></td></tr>
 
</table>
===crystal structure of heterohexameric TusBCD proteins, which are crucial for the tRNA modification===
== Function ==
 
[https://www.uniprot.org/uniprot/TUSD_ECOLI TUSD_ECOLI] Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.<ref>PMID:16387657</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_16472754}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 16472754 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/2d1p_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16472754}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2D1P is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1P OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d1p ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex., Numata T, Fukai S, Ikeuchi Y, Suzuki T, Nureki O, Structure. 2006 Feb;14(2):357-66. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16472754 16472754]
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Fukai, S.]]
[[Category: Fukai S]]
[[Category: Ikeuchi, Y.]]
[[Category: Ikeuchi Y]]
[[Category: Numata, T.]]
[[Category: Numata T]]
[[Category: Nureki, O.]]
[[Category: Nureki O]]
[[Category: Suzuki, T.]]
[[Category: Suzuki T]]
[[Category: Structural genomic]]
[[Category: Sulfur transfer]]
[[Category: Trna modification]]
 
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Retrieved from "https://proteopedia.org/2d1p"