2dx8: Difference between revisions

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[[Image:2dx8.jpg|left|200px]]<br /><applet load="2dx8" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2dx8, resolution 2.70&Aring;" />
'''Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus'''<br />


==About this Structure==
==Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus==
2DX8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DX8 OCA].  
<StructureSection load='2dx8' size='340' side='right'caption='[[2dx8]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DX8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dx8 OCA], [https://pdbe.org/2dx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dx8 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYGO1_MOUSE PYGO1_MOUSE] Involved in signal transduction through the Wnt pathway (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dx8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dx8 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Padmanabhan B]]
[[Category: Padmanabhan, B.]]
[[Category: Yokoyama S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: bcl9/lgs interactor]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: phd finger]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:03:40 2008''
Retrieved from "https://proteopedia.org/2dx8"