2dx8: Difference between revisions
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New page: left|200px<br /><applet load="2dx8" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dx8, resolution 2.70Å" /> '''Crystal Structure An... |
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== | ==Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus== | ||
<StructureSection load='2dx8' size='340' side='right'caption='[[2dx8]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2dx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DX8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dx8 OCA], [https://pdbe.org/2dx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dx8 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PYGO1_MOUSE PYGO1_MOUSE] Involved in signal transduction through the Wnt pathway (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dx8_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dx8 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Padmanabhan B]] | |||
[[Category: Padmanabhan | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 13:48, 13 March 2024
Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus
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