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[[Image:2e1b.png|left|200px]]


{{STRUCTURE_2e1b|  PDB=2e1b  |  SCENE=  }}
==Crystal structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii==
 
<StructureSection load='2e1b' size='340' side='right'caption='[[2e1b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Crystal structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2e1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E1B FirstGlance]. <br>
{{ABSTRACT_PUBMED_17327676}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1b OCA], [https://pdbe.org/2e1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1b RCSB], [https://www.ebi.ac.uk/pdbsum/2e1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1b ProSAT], [https://www.topsan.org/Proteins/RSGI/2e1b TOPSAN]</span></td></tr>
[[2e1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1B OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ALAXM_PYRHO ALAXM_PYRHO] Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala).<ref>PMID:17327676</ref>  
<ref group="xtra">PMID:017327676</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e1/2e1b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e1b ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Fukunaga, R.]]
[[Category: Fukunaga R]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Hydrolase]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Trans-editing enzyme]]
[[Category: Zinc-binding motif]]