3a6o: Difference between revisions

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{{Seed}}
[[Image:3a6o.jpg|left|200px]]


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==Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase 2/acarbose complex==
The line below this paragraph, containing "STRUCTURE_3a6o", creates the "Structure Box" on the page.
<StructureSection load='3a6o' size='340' side='right'caption='[[3a6o]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3a6o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vfk 1vfk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A6O FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARE:ACARBOSE+DERIVED+PENTASACCHARIDE'>ARE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_3a6o| PDB=3a6o |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6o OCA], [https://pdbe.org/3a6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a6o RCSB], [https://www.ebi.ac.uk/pdbsum/3a6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NEPU2_THEVU NEPU2_THEVU] Hydrolyzes pullulan efficiently but only a small amount of starch. Endohydrolysis of 1,4-alpha-glucosidic linkages in pullulan to form panose. Cleaves also (1-6)-alpha-glucosidic linkages to form maltotriose.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/3a6o_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a6o ConSurf].
<div style="clear:both"></div>


===Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase 2/acarbose complex===
==See Also==
 
*[[Amylase 3D structures|Amylase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15138257}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15138257 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15138257}}
 
==About this Structure==
3A6O is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vfk 1vfk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6O OCA].
 
==Reference==
<ref group="xtra">PMID:15138257</ref><references group="xtra"/>
[[Category: Neopullulanase]]
[[Category: Thermoactinomyces vulgaris]]
[[Category: Thermoactinomyces vulgaris]]
[[Category: Kamitori, S.]]
[[Category: Kamitori S]]
[[Category: Mizuno, M.]]
[[Category: Mizuno M]]
[[Category: Ohtaki, A.]]
[[Category: Ohtaki A]]
[[Category: Sakano, Y.]]
[[Category: Sakano Y]]
[[Category: Tonozuka, T.]]
[[Category: Tonozuka T]]
[[Category: Acarbose]]
[[Category: Amylase]]
[[Category: Calcium]]
[[Category: Carbohydrate metabolism]]
[[Category: Complex]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Metal-binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:39:08 2009''
Retrieved from "https://proteopedia.org/3a6o"