1amn: Difference between revisions

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[[Image:1amn.png|left|200px]]


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==TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE==
The line below this paragraph, containing "STRUCTURE_1amn", creates the "Structure Box" on the page.
<StructureSection load='1amn' size='340' side='right'caption='[[1amn]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1amn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AMN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAF:M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE'>NAF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1amn|  PDB=1amn  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1amn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1amn OCA], [https://pdbe.org/1amn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1amn RCSB], [https://www.ebi.ac.uk/pdbsum/1amn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1amn ProSAT]</span></td></tr>
 
</table>
===TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE===
== Function ==
 
[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[1amn]] is a 1 chain structure of [[Acetylcholinesterase]] with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMN OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/1amn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1amn ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Acetylcholinesterase]]
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
[[Category: Acetylcholinesterase]]
__TOC__
[[Category: Torpedo californica]]
</StructureSection>
[[Category: Harel, M.]]
[[Category: Large Structures]]
[[Category: Silman, I.]]
[[Category: Tetronarce californica]]
[[Category: Sussman, J L.]]
[[Category: Harel M]]
[[Category: Alternative splicing]]
[[Category: Silman I]]
[[Category: Glycoprotein]]
[[Category: Sussman JL]]
[[Category: Gpi-anchor]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Muscle]]
[[Category: Nerve]]
[[Category: Neurotransmitter degradation]]
[[Category: Serine esterase]]
[[Category: Signal]]
[[Category: Synapse]]
Retrieved from "https://proteopedia.org/1amn"