3q91: Difference between revisions
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==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)== | ==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)== | ||
<StructureSection load='3q91' size='340' side='right' caption='[[3q91]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='3q91' size='340' side='right'caption='[[3q91]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q91 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [https://pdbe.org/3q91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [https://www.ebi.ac.uk/pdbsum/3q91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q91 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Berglund H]] | |||
[[Category: Berglund | [[Category: Bountra C]] | ||
[[Category: Bountra | [[Category: Collins R]] | ||
[[Category: Collins | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Ekblad T]] | ||
[[Category: Ekblad | [[Category: Flodin S]] | ||
[[Category: Flodin | [[Category: Flores A]] | ||
[[Category: Flores | [[Category: Graslund S]] | ||
[[Category: Graslund | [[Category: Hammarstrom M]] | ||
[[Category: Hammarstrom | [[Category: Johansson I]] | ||
[[Category: Johansson | [[Category: Karlberg T]] | ||
[[Category: Karlberg | [[Category: Kol S]] | ||
[[Category: Kol | [[Category: Kotenyova T]] | ||
[[Category: Kotenyova | [[Category: Kouznetsova E]] | ||
[[Category: Kouznetsova | [[Category: Moche M]] | ||
[[Category: Moche | [[Category: Nordlund P]] | ||
[[Category: Nordlund | [[Category: Nyman T]] | ||
[[Category: Nyman | [[Category: Persson C]] | ||
[[Category: Persson | [[Category: Schuler H]] | ||
[[Category: Schutz P]] | |||
[[Category: Schuler | [[Category: Siponen MI]] | ||
[[Category: Schutz | [[Category: Thorsell AG]] | ||
[[Category: Siponen | [[Category: Tresaugues L]] | ||
[[Category: Thorsell | [[Category: Van Der Berg S]] | ||
[[Category: Tresaugues | [[Category: Wahlberg E]] | ||
[[Category: | [[Category: Weigelt J]] | ||
[[Category: | [[Category: Welin M]] | ||
[[Category: | |||
[[Category: | |||
Latest revision as of 11:37, 14 March 2024
Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
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