3qij: Difference between revisions

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[[Image:3qij.jpg|left|200px]]


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==Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R==
The line below this paragraph, containing "STRUCTURE_3qij", creates the "Structure Box" on the page.
<StructureSection load='3qij' size='340' side='right'caption='[[3qij]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3qij]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QIJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
{{STRUCTURE_3qij|  PDB=3qij  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qij OCA], [https://pdbe.org/3qij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qij RCSB], [https://www.ebi.ac.uk/pdbsum/3qij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qij ProSAT]</span></td></tr>
 
</table>
===Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R===
== Disease ==
 
[https://www.uniprot.org/uniprot/EPB41_HUMAN EPB41_HUMAN] Hereditary elliptocytosis. The disease is caused by variants affecting the gene represented in this entry.
 
== Function ==
==About this Structure==
[https://www.uniprot.org/uniprot/EPB41_HUMAN EPB41_HUMAN] Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).<ref>PMID:23870127</ref>
[[3qij]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QIJ OCA].  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M.]]
[[Category: Bountra C]]
[[Category: Nedyalkova, L.]]
[[Category: Edwards AM]]
[[Category: Park, H.]]
[[Category: Nedyalkova L]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Tong, Y.]]
[[Category: Tong Y]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Zhong, N.]]
[[Category: Zhong N]]
Retrieved from "https://proteopedia.org/3qij"