3qmd: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qmd is ON HOLD Authors: Lam, R., Xu, C., Bian, C. B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C. H., Edwards, A. M., Bochkarev, A., Min, J... |
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==Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1== | |||
<StructureSection load='3qmd' size='340' side='right'caption='[[3qmd]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qmd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QMD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qmd OCA], [https://pdbe.org/3qmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qmd RCSB], [https://www.ebi.ac.uk/pdbsum/3qmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qmd ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bian CB]] | |||
[[Category: Bochkarev A]] | |||
[[Category: Bountra C]] | |||
[[Category: Edwards AM]] | |||
[[Category: Kania J]] | |||
[[Category: Lam R]] | |||
[[Category: Min J]] | |||
[[Category: Weigelt J]] | |||
[[Category: Xu C]] | |||
Latest revision as of 11:51, 14 March 2024
Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
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