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==Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site==
==Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site==
<StructureSection load='3r0d' size='340' side='right' caption='[[3r0d]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3r0d' size='340' side='right'caption='[[3r0d]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3r0d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R0D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3r0d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R0D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PXN:(2S)-1-[3-{[(2R)-2-HYDROXYPROPYL]OXY}-2,2-BIS({[(2R)-2-HYDROXYPROPYL]OXY}METHYL)PROPOXY]PROPAN-2-OL'>PXN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o7u|3o7u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PXN:(2S)-1-[3-{[(2R)-2-HYDROXYPROPYL]OXY}-2,2-BIS({[(2R)-2-HYDROXYPROPYL]OXY}METHYL)PROPOXY]PROPAN-2-OL'>PXN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">codA, b0337, JW0328 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0d OCA], [https://pdbe.org/3r0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0d RCSB], [https://www.ebi.ac.uk/pdbsum/3r0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0d ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytosine_deaminase Cytosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.1 3.5.4.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0d OCA], [http://pdbe.org/3r0d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3r0d RCSB], [http://www.ebi.ac.uk/pdbsum/3r0d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CODA_ECOLI CODA_ECOLI]


==See Also==
==See Also==
*[[Deaminase|Deaminase]]
*[[Deaminase 3D structures|Deaminase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cytosine deaminase]]
[[Category: Escherichia coli K-12]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Fedorov, A A]]
[[Category: Fedorov AA]]
[[Category: Fedorov, E V]]
[[Category: Fedorov EV]]
[[Category: Hitchcock, D]]
[[Category: Hitchcock D]]
[[Category: Kamat, S]]
[[Category: Kamat S]]
[[Category: Raushel, F M]]
[[Category: Raushel FM]]
[[Category: Hydrolase]]
[[Category: Tim barrel]]

Latest revision as of 12:04, 14 March 2024

Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site

3r0d, resolution 1.50Å

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