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==Pseudomonas aeruginosa DapD (PA3666) in complex with CoA and succinate==
==Pseudomonas aeruginosa DapD (PA3666) in complex with CoA and succinate==
<StructureSection load='3r5c' size='340' side='right' caption='[[3r5c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3r5c' size='340' side='right'caption='[[3r5c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3r5c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R5C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3r5c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R5C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r5a|3r5a]], [[3r5b|3r5b]], [[3r5d|3r5d]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapD, PA3666 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r5c OCA], [https://pdbe.org/3r5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r5c RCSB], [https://www.ebi.ac.uk/pdbsum/3r5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r5c ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2,3,4,5-tetrahydropyridine-2,6-dicarboxylate_N-succinyltransferase 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.117 2.3.1.117] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r5c RCSB], [http://www.ebi.ac.uk/pdbsum/3r5c PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DAPD_PSEAE DAPD_PSEAE] Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. It can only accept L-2 aminopimelate as substrate.<ref>PMID:22359568</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase]]
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Sandalova, T]]
[[Category: Sandalova T]]
[[Category: Schneider, G]]
[[Category: Schneider G]]
[[Category: Schnell, R]]
[[Category: Schnell R]]
[[Category: Transferase]]

Latest revision as of 12:10, 14 March 2024

Pseudomonas aeruginosa DapD (PA3666) in complex with CoA and succinate

3r5c, resolution 2.40Å

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