3rbw: Difference between revisions

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[[Image:3rbw.jpg|left|200px]]


<!--
==Crystal structure of Spire KIND domain==
The line below this paragraph, containing "STRUCTURE_3rbw", creates the "Structure Box" on the page.
<StructureSection load='3rbw' size='340' side='right'caption='[[3rbw]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rbw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbw OCA], [https://pdbe.org/3rbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbw RCSB], [https://www.ebi.ac.uk/pdbsum/3rbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbw ProSAT]</span></td></tr>
{{STRUCTURE_3rbw|  PDB=3rbw  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of Spire KIND domain===
[https://www.uniprot.org/uniprot/SPIR1_HUMAN SPIR1_HUMAN] Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.<ref>PMID:11747823</ref> <ref>PMID:21620703</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
[[3rbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBW OCA].  
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Eck, M J.]]
[[Category: Large Structures]]
[[Category: Kreutz, B.]]
[[Category: Eck MJ]]
[[Category: Lu, J.]]
[[Category: Kreutz B]]
[[Category: Quinlan, M E.]]
[[Category: Lu J]]
[[Category: Rodal, A A.]]
[[Category: Quinlan ME]]
[[Category: Toms, A V.]]
[[Category: Rodal AA]]
[[Category: Vizcarra, C L.]]
[[Category: Toms AV]]
[[Category: Zheng, W.]]
[[Category: Vizcarra CL]]
[[Category: Actin nucleator]]
[[Category: Zheng W]]
[[Category: C-lobe of protein kinase]]
[[Category: Fmn-family formin]]
[[Category: Protein binding]]

Latest revision as of 12:17, 14 March 2024

Crystal structure of Spire KIND domain

3rbw, resolution 3.20Å

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